- In Blue Valentine (2010), he had co-stars Ryan Gosling and Michelle Williams live together for a month in house that would be their on-screen home.
- Such is his dedication to creating authentic performances from his actors, that at least two real-life couplings have emerged from his films; Ryan Gosling and Eva Mendes met on the set of The Place Beyond the Pines (2012) and now have two daughters together. Michael Fassbender and Alicia Vikander entered a relationship while filming The Light Between Oceans (2016) and married in late 2017. Cianfrance had asked Gosling to make a move on Michelle Williams when filming the relationship drama Blue Valentine (2010) but she rejected his advances.
- Friend of Ryan Gosling's since 2006 and has directed him in two films.
- Directed one Oscar nominated performance: Michelle Williams in Blue Valentine (2010).
- Cianfrance is a drummer and has blown his eardrums out. He has tinnitus, a constant ringing in his ears. His condition inspired him to direct the film "Metalhead", which was not developed.
- Acts in Towheads (2013) which was directed by wife Shannon Plumb, who also stars in it, along with their sons Walker and Cody.
- Has directed one Emmy Award-winning performance: Mark Ruffalo in I Know This Much Is True (2020).
- Born on exactly the same date as Tiffani Thiessen of "Saved By the Bell" fame.
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