Anisodamine

Anisodamine
Clinical data
ATC code	None;
Identifiers
	IUPAC name [(1S,3S,5S,7S)-7-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenyl-propanoate;
CAS Number	55869-99-3;
PubChem CID	183088;
ChemSpider	159209 ;
UNII	01343Q8EL8;
ECHA InfoCard	100.164.962
Chemical and physical data
Formula	C17H23NO4
Molar mass	305.37 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O[C@@H]1C[C@@H]2N(C)[C@H](C1)C[C@@H]2O)[C@@H](c3ccccc3)CO;
	InChI InChI=1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13+,14-,15+,16+/m1/s1 ; Key:WTQYWNWRJNXDEG-LEOABGAYSA-N ;
	(verify)

Anisodamine, also known as 7β-hydroxyhyoscyamine, is an anticholinergic and α₁-adrenergic receptor [[alpha-adrenergic antagonist] used in the treatment of acute circulatory shock in China.^[1] It is also a naturally occurring tropane alkaloid found in some plants of the Solanaceae family.^[2]

References

^ Varma DR, Yue TL (1986). "Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats". British Journal of Pharmacology. 87 (3): 587–94. PMC 1916562. PMID 2879586. {{cite journal}}: Unknown parameter |month= ignored (help)
^ Zhang WW, Song MK, Cui YY; et al. (2008). "Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine". Neuroscience Letters. 443 (3): 241–5. doi:10.1016/j.neulet.2008.07.048. PMID 18672024. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

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