Primary cutaneous amyloidosis
| Primary cutaneous amyloidosis | |
|---|---|
| Other names | Primary localized cutaneous amyloidosis[1] |
 | |
| Macular amyloidosis, located on the right lumbar region of the back | |
| Specialty | Dermatology |
Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.[2][3] This type of amyloidosis has been divided into the following types:[4]: 520
- Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.[4]: 521 Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum.[5]
- Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.[4]: 521
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Histopathology of lichen amyloidosis, with subepithelial Congo red-positive deposits -
Lichen amyloidosis on a 56-year-old male's leg -
Lichen amyloidosis on a 56-year-old male's leg
- Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.[4]: 521
See also
References
- ^ "Primary cutaneous amyloidosis | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 18 April 2019.
- ^ "Amyloid".
- ^ Arita K, South AP, Hans-Filho G, et al. (January 2008). "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis". Am. J. Hum. Genet. 82 (1): 73–80. doi:10.1016/j.ajhg.2007.09.002. PMC 2253984. PMID 18179886.
- ^ a b c d James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
- ^ Lichen amyloidosis of the auricular concha Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology
External links
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