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. 2011 Apr;31(4):637-40.

[Value of deep small-bowel endoscopy in the diagnosis of Crohn's disease]

[Article in Chinese]
Shao-Heng Zhang  1 , Jun Xu, Qing Qing, Fa-Chao Zhi, Yang Bai, Zhi-Min Xu, Bo Jiang, Ya-Li Zhang, Ye Chen
Affiliations
  • PMID: 21515459

[Value of deep small-bowel endoscopy in the diagnosis of Crohn's disease]

[Article in Chinese]
Shao-Heng Zhang et al. Nan Fang Yi Ke Da Xue Xue Bao. 2011 Apr.

Abstract

Objective: To evaluate the value of deep small-bowel endoscopy (DSBE) in the diagnosis of Crohns disease (CD).

Methods: The endoscopic and clinical data of 54 patients with CD receiving capsule endoscopy (CE) and double-balloon enteroscopy (DBE) between January, 2004 and December, 2008 were summarized and analyzed retrospectively.

Results: The main indications for DSBE in our series were suspected CD (42.6%) and obscure gastrointestinal bleeding (25.9%). DSBE was obviously superior to barium imaging. The detection rate of CD was significantly higher with DSBE (92.6%) than with ileocolonoscopy (75.9%, P=0.017), and DSBE provides much more detailed descriptions of specific endoscopic features such as segmental distribution and lumen changes. DSBE significantly improve the diagnostic efficiency, giving priority to offer a guide and raise suspected diagnosis for CD.

Conclusion: DSBE is a valuable modality for detecting CD lesions in the jejunum and ileum and for evaluating lesion involvement and severity. The combination with a comprehensive analysis of routine imaging findings, gastro endoscopy, and clinical data can further enhance the diagnostic efficiency of DSBE.

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