Simple transposon

A simple transposon also called "conservative transposon" is an insertion sequence (IS element) that contains its own coding transposase between the short, inverted, repeated sequences that flank (present) its gene coding region. Transposase is responsible for excision and transfer while resolvase is responsible for resolution of the transfer.^[1]

Simple transposition is also called cut-and-paste transposition because the element is cut out of its original site and pasted into a new one.^[2]

References

^ Guo, Y; Park, JM; Cui, B; Humes, E; Gangadharan, S; Hung, S; FitzGerald, PC; Hoe, KL; Grewal, SI; Craig, NL; Levin, HL (2013). "Integration profiling of gene function with dense maps of transposon integration". Genetics. 195 (2): 599–609. doi:10.1534/genetics.113.152744. PMC 3781984. PMID 23893486.
^ Largaespada, D. A. (2003). "Generating and manipulating transgenic animals using transposable elements". Reproductive Biology and Endocrinology. 1: 80. doi:10.1186/1477-7827-1-80. PMC 280724. PMID 14613544.

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[1] Guo, Y; Park, JM; Cui, B; Humes, E; Gangadharan, S; Hung, S; FitzGerald, PC; Hoe, KL; Grewal, SI; Craig, NL; Levin, HL (2013). "Integration profiling of gene function with dense maps of transposon integration". Genetics. 195 (2): 599–609. doi:10.1534/genetics.113.152744. PMC 3781984. PMID 23893486.

[2] Largaespada, D. A. (2003). "Generating and manipulating transgenic animals using transposable elements". Reproductive Biology and Endocrinology. 1: 80. doi:10.1186/1477-7827-1-80. PMC 280724. PMID 14613544.

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