MAGT1

MAGT1
Identifikatori
Aliasi	MAGT1
Vanjski ID-jevi	OMIM: 300715 MGI: 1914325 HomoloGene: 100678 GeneCards: MAGT1
Lokacija gena (čovjek)
Hrom.	Hromosom X
Kraj	77,899,271 bp
Lokacija gena (miš)
Hrom.	Hromosom X (miš)
Kraj	105,055,512 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• magnesium ion transmembrane transporter activity; • dolichyl-diphosphooligosaccharide-protein glycotransferase activity;
Ćelijska komponenta	• integral component of membrane; • oligosaccharyltransferase complex; • ćelijska membrana; • integral component of plasma membrane; • membrana; • endoplasmic reticulum membrane; • azurophil granule membrane; • Endoplazmatski retikulum;
Biološki proces	• magnesium ion transport; • protein N-linked glycosylation; • kognitivna funkcija; • transmembrane transport; • magnesium ion transmembrane transport; • neutrophil degranulation; • GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation; • protein N-linked glycosylation via asparagine; • GO:0015915 transport;
	Izvori:Amigo / QuickGO
Ortolozi
	84061
	67075
	ENSG00000102158
	ENSMUSG00000031232
	Q9H0U3
	Q9CQY5
	NM_032121; NM_001367916
	NM_001190409; NM_025952; NM_001377002; NM_001377003
	NP_115497; NP_001354845
	NP_001177338; NP_080228; NP_001363931; NP_001363932
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Magnezijski transportni protein 1 je protein koji je kod ljudi kodiran genom MAGT1.^[5]^[6]

Funkcije ortologa

Molekulska funkcija • aktivnost transmembranskog transportera magnezijevih iona

• aktivnost glikotransferaze dolihil-difosfooligosaccharid-protein

Ćelijska komponenta • integralna komponenta membrane

• kompleks oligosahariltransferaze • ćelijska membrane • integralna komponenta plazmatske membrane • membrana • membrana endoplazmatskog retikuluma • membrana azurofilnih granula • endoplazmatski retikulum

Biološki proces • transport magnezijumovih jona • proteinska N-vezana glikozilacija • transmembranski transport • transmembranski transport magnezijevih iona • degranulacija neutrofila • glikozilacija proteina • proteinska N-vezana glikozilacija preko asparagina • transport

Izvori: Amigo / QuickGO
Molekulska funkcija • aktivnost transmembranskog transportera magnezijskih iona

• aktivnost glikotransferaze dolihil-difosfooligosaccharid-proteina

Ćelijska komponenta • integralna komponenta membrane

• kompleks oligosahariltransferaze • ćelijske membrane • integralna komponenta plazmatske membrane • membrana • membrana endoplazmatskog retikuluma • membrana azurofilnih granula • endoplazmatski retikulum

Biološki proces • transport magnezijskih iona

• proteinska N-vezana glikozilacija • transmembranski transport • transmembranski transport magnezijevih iona • degranulacija neutrofila • glikozilacija proteina • proteinska N-vezana glikozilacija preko asparagina • transport

Izvori: Amigo/QuickGO

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102158 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031232 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Goytain A, Quamme GA (maj 2005). "Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties". BMC Genomics. 6 (1): 48. doi:10.1186/1471-2164-6-48. PMC 1129089. PMID 15804357.
^ "Entrez Gene: RP11-217H1.1 implantation-associated protein".

Dopunska literatura

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Yu Y, Zhang C, Zhou G, et al. (2001). "Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs". Genome Res. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R (2003). "Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties". Mol. Cell. 12 (1): 101–11. doi:10.1016/S1097-2765(03)00243-0. PMID 12887896.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Shibatani T, David LL, McCormack AL, et al. (2005). "Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits". Biochemistry. 44 (16): 5982–92. doi:10.1021/bi047328f. PMID 15835887.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102158 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031232 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15804357-5] Goytain A, Quamme GA (maj 2005). "Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties". BMC Genomics. 6 (1): 48. doi:10.1186/1471-2164-6-48. PMC 1129089. PMID 15804357.

[entrez-6] "Entrez Gene: RP11-217H1.1 implantation-associated protein".

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