Fosfinotricin acetiltransferaza
| Fosfinotricin acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.183 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fosfinotricin acetiltransferaza (EC 2.3.1.183, PAT, PPT acetiltransferaza, Pt-N-acetiltransferaza, ac-Pt) je enzim sa sistematskim imenom acetil-KoA:fosfinotricin N-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + fosfinotricin KoA + N-acetilfosfinotricin
Supstrat, fosfinotricin, se koristi kao neselektivni herbicid i potentni inhibitor enzima EC 6.3.1.2, glutamat---amonijak ligaze, koji je ključni enzim azotnog metabolizma kod biljki.
- ↑ Botterman, J., Gosselé, V., Thoen, C. and Lauwereys, M. (1991). „Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins”. Gene 102: 33-37. PMID 1864506.
- ↑ Dröge-Laser, W., Siemeling, U., Pühler, A. and Broer, I. (1994). „The metabolites of the herbicide L-phosphinothricin (glufosinate) (identification, stability, and mobility in transgenic, herbicide-resistant, and untransformed plants)”. Plant Physiol. 105: 159-166. PMID 12232195.
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