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About

⭐ Biomanufacturing and digital health innovation enthusiast
⭐ Growth Strategist
⭐…

Articles by Gloria

  • Lessons learnt on effective communication
    May 31, 2017

    Lessons learnt on effective communication

    My company just completed the construction phase on a contract manufacturing cell processing facility in Hong Kong and…

  • Delays – Projects 101
    Feb 24, 2017

    Delays – Projects 101

    Delays - a word most project managers in the world hear and shrivel a little inside. Whilst it is pretty much inherent…

    4 Comments
  • The many little things that haunt you in a fit-out facility project
    Jan 18, 2017

    The many little things that haunt you in a fit-out facility project

    We are in the construction phase of fitting out a cell processing facility in Hong Kong Science Park and around one…

Activity

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Experience & Education

  • PA Consulting

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Volunteer Experience

  • Science Innovation Union Graphic

    Events Lead (London team)

    Science Innovation Union

    - 8 months

    Science and Technology

  • Oxford University Biotech Society Graphic

    Events Organiser

    Oxford University Biotech Society

    - 1 year 3 months

    Science and Technology

  • Committee Member

    IChemE Biochemical Engineering Special Interest Group

    - Present 5 years 6 months

    Science and Technology

  • Institution of Chemical Engineers (IChemE) Graphic

    Committee member (Thames Valley Member Group, National Young Members Committee)

    Institution of Chemical Engineers (IChemE)

    - Present 7 years 3 months

    Science and Technology

  • Committee Member

    Women in Engineering Oxford

    - 1 year

    Science and Technology

  • Royal Academy of Engineering Graphic

    Diversity Leadership Subgroup - Young People/early career group

    Royal Academy of Engineering

    - 1 year 3 months

    Science and Technology

    - Act as a sounding board for diversity leadership group ideas

  • Institution of Chemical Engineers (IChemE) Graphic

    UCL representative

    Institution of Chemical Engineers (IChemE)

    - 3 years 6 months

    Science and Technology

    - Attended monthly branch meetings
    - Facilitated the set up of the Young Members Group London among UCL, Imperial and London South Bank University
    - Organised horizons talks, socials, forums and field trips for young chemical engineers in London
    - Promoted IChemE events in campus and through the young member group
    - Hosted annual women in engineering events

  • Treasurer and Chairperson of Biochemical Engineering branch

    UCL Student Society of Women Engineers

    - 1 year 11 months

    Science and Technology

    - Promote society activities within the biochemical engineering department
    - Set up and manage the society account
    - Organize events specifically for female engineers, e.g. 'Celebrating women in biochemical and chemical engineering' event on 18th Feb 2014

  • Homeless Meals Volunteer

    Central London Rough Sleepers Committee

    - 6 years 2 months

    Civil Rights and Social Action

    Regular volunteer at Homeless Meals which is organised by volunteers. The meals are currently hosted twice a month at St.Mary's Church, Marylebone and St.Peter's Church nr. Oxford St.
    A nourishing hot 2 course meal is served and a friendly, safe environment created for guests to share conversation, and unwind for a few hours.

  • IChemE London Young Members Forum Graphic

    Founder and Chairperson

    IChemE London Young Members Forum

    - 1 year 10 months

    Science and Technology

    - Organized horizons talks and socials for young chemical engineers in London
    - Networked with IChemE to bring focus on provision of internship and placement opportunities to young engineers
    - Promotion of events in campus and through social media

Publications

Projects

  • Masters Project - Process Economics: Whole bioprocess optimization for the manufacture of biosimilar mAbs

    -

    The aim of the project is to extend the existing decisional tool (on a C# platform) with process economics and optimization features to address various challenges in multi-product facility design. Multiobjective optimization and multi-criteria decision making techniques are used to evaluate the tradeoff between process time and cost of goods for chromatography operations. Extension of the model will cover single use manufacturing, perfusion culture and continuous chromatography.

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  • 3rd Year Design Project - Comparative analysis of Single-Use and Stainless Steel flowsheets for production of antibody fragment for treatment of colorectal cancer using E. Coli

    -

    - A process was defined to produce the chosen antibody fragment using E. Coli as the expression system for single-use and stainless steel equipment
    - Mass balances and process economics were subsequently evaluated
    - cGMP facility layout, familiarised with GMP guidelines
    - P&ID and mechanical drawing of a fermenter were produced using AUTOCAD

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  • Analysis of Pichia fermentation results

    -

    Laboratory work before term starts to analyse sorbitol content of samples taken throughout the fermentation performed previously and to analyse intracellular and extracellular protein before and after sonication of samples.

    Skills: D-Sorbitol Colorimetric Assay, SDS-PAGE gel electrophoresis

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  • Temperature characterization of a thermomixer for subsequent Fab' extraction from E. Coli

    -

    The project aims to characterise an Eppendorf thermomixer before usage in a masters project for Fab' extraction in E. Coli.
    Temperature profiles of different regions were analysed.

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  • Effect of periplasmic heat extraction temperature and incubation time on Fab' purification

    -

    The research project investigates the effect of periplasmic heat extraction temperature and incubation time on Fab' purification. Scale down heat extraction and chromatography experiments were performed on a robotic platform, involving PhyTips and HPLC experiments.
    Further analytical work quantifying the product and contaminants involved SDS-PAGE gel electrophoresis, high throughput assays (BCA and Picogreen assays).
    The project was supervised by Simyee Kong, UCL post…

    The research project investigates the effect of periplasmic heat extraction temperature and incubation time on Fab' purification. Scale down heat extraction and chromatography experiments were performed on a robotic platform, involving PhyTips and HPLC experiments.
    Further analytical work quantifying the product and contaminants involved SDS-PAGE gel electrophoresis, high throughput assays (BCA and Picogreen assays).
    The project was supervised by Simyee Kong, UCL post doctorate.
    Skills: HPLC, PhyTip, SDS-PAGE gel electrophoresis, BCA Assay, Picogreen Assay

  • Industrial Challenges Associated with Pichia Pastoris Expression Systems: Do High Cell Densities Overburden Primary Recovery?

    -

    A study on the behavior of Pichia pastoris under mixed (sorbitol and methanol) feed and pure methanol feed over course of fermentation. Pilot scale centrifugation was carried out on Baker’s yeast cell mixtures of various densities to mimic the various stages of upstream fermentation.
    The project was led by UCL 2nd year PhD students:
    Stefan Woodhouse, Alma Antemie and Ben Weil
    Skills: P. pastoris fermentation, pilot scale centrifugation

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Honors & Awards

  • CRMI Technology Centre Studentship

    University of Oxford Department of Engineering Science

  • Jacobs Engineering Design Project Prize for Outstanding Individual Contribution

    UCL Department of Biochemical Engineering, Jacobs Engineering

    Commendation for individual contribution in 3rd year design project

  • Chair Prize

    IChemE London and SouthEast Regional Group

    Commendation for contribution to IChemE London and SouthEast Regional Group

  • Head of Department Commendation Award

    UCL Department of Biochemical Engineering

    Commendation for contribution to the department

Languages

  • Chinese (Cantonese)

    Native or bilingual proficiency

  • Chinese (Mandarin)

    Native or bilingual proficiency

  • English

    Native or bilingual proficiency

  • German

    Elementary proficiency

Organizations

  • Institution of Chemical Engineers

    Associate Member

    - Present

  • Healthcare Businesswomen's Association

    -

    -

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